Millions of people rely on traditional antidepressants for relief, but what happens when they stop working—or never worked at all? Ketamine therapy offers a groundbreaking alternative. Here’s how it compares to conventional treatments.

Mechanism of Action

  • Traditional Antidepressants: Increase serotonin levels over time
  • Ketamine: Targets the glutamate system and promotes rapid synaptic growth

Onset of Relief

  • Antidepressants may take 2–6 weeks to show benefits
  • Ketamine can reduce symptoms in as little as 1–3 sessions

Efficacy for Treatment-Resistant Depression

Studies show ketamine is highly effective for patients who haven’t responded to traditional options—making it a game-changer in modern psychiatry.

Side-by-Side Comparison

Feature Ketamine Therapy Traditional Antidepressants
Time to Relief Hours to Days Weeks
Works for Resistant Cases Yes Often Not
Administration Method IV Infusion Oral
Target Pathway Glutamate/NMDA Serotonin/Norepinephrine

The Bottom Line

If you haven’t found success with antidepressants, ketamine may offer new hope. Contact Dr. Jon Deam to see if it’s right for you.

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